Very much so. There are two extremes.middle, are the crafty beers a lower % markup in general than your PBR etc options?
A can of PBR costs 50c and is $3.50, 7X markup.
A bottle of 2016 Goose Island Madame Rose costs $17.05 and is $35, barely a 2X markup.
Between those two extremes is an almost perfect line, if cost is one axis and markup is the other, connecting them.
Sometimes scarcity plays a role. My draft handles all (except for our house beer that I brewed in collaboration with a local brewery) rotate--when the keg empties, the line becomes a different beer. When we put stuff like FFF Zombie Dust or Goose BCS or Abraxas or something that gets beer nerds salivating I mark that [expletive] up like crazy. Like 7, 8, 10 times. Because those guys will happily pay it. It's even part of the game, y'know? Come in, drink a BCS in June, pay $9 for 5oz of it, then check that [expletive] in on Untappd so the other beer nerds know you are totally cool.